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Non-natural 3-Arylmorpholino-β-amino Acid as a PPII Helix Inducer

[Image: see text] A new non-natural β-amino acid, named 3-Ar-β-Morph, was designed and synthesized via a regio- and diastereoselective Pd-catalyzed C(sp(3))H-arylation of the corresponding 2S,6S-(6-methoxymorpholin-2-yl)carboxylic acid, readily available from glucose. According to the computational...

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Detalles Bibliográficos
Autores principales:	Vaghi, Francesco, Bucci, Raffaella, Clerici, Francesca, Contini, Alessandro, Gelmi, M. Luisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009597/ https://www.ncbi.nlm.nih.gov/pubmed/32790435 http://dx.doi.org/10.1021/acs.orglett.0c02331

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