Pre-complexation of talin and vinculin without tension is required for efficient nascent adhesion maturation

Talin and vinculin are mechanosensitive proteins that are recruited early to integrin-based nascent adhesions (NAs). In two epithelial cell systems with well-delineated NA formation, we find these molecules concurrently recruited to the subclass of NAs maturing to focal adhesions. After the initial...

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Detalles Bibliográficos
Autores principales: Han, Sangyoon J, Azarova, Evgenia V, Whitewood, Austin J, Bachir, Alexia, Guttierrez, Edgar, Groisman, Alex, Horwitz, Alan R, Goult, Benjamin T, Dean, Kevin M, Danuser, Gaudenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009661/
https://www.ncbi.nlm.nih.gov/pubmed/33783351
http://dx.doi.org/10.7554/eLife.66151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009661/
https://www.ncbi.nlm.nih.gov/pubmed/33783351
http://dx.doi.org/10.7554/eLife.66151

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