Cargando…

Noradrenergic Suppression of Persistent Firing in Hippocampal CA1 Pyramidal Cells through cAMP-PKA Pathway

Persistent firing is believed to be a cellular correlate of working memory. While the effects of noradrenaline (NA) on working memory have widely been described, its effect on the cellular mechanisms of persistent firing remains largely unknown. Using in vitro intracellular recordings, we demonstrat...

Descripción completa

Detalles Bibliográficos
Autores principales: Valero-Aracama, Maria Jesus, Reboreda, Antonio, Arboit, Alberto, Sauvage, Magdalena, Yoshida, Motoharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009666/
https://www.ncbi.nlm.nih.gov/pubmed/33637539
http://dx.doi.org/10.1523/ENEURO.0440-20.2020