The dimeric Golgi protein Gorab binds to Sas6 as a monomer to mediate centriole duplication

The duplication and ninefold symmetry of the Drosophila centriole requires that the cartwheel molecule, Sas6, physically associates with Gorab, a trans-Golgi component. How Gorab achieves these disparate associations is unclear. Here, we use hydrogen–deuterium exchange mass spectrometry to define Go...

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Detalles Bibliográficos
Autores principales: Fatalska, Agnieszka, Stepinac, Emma, Richter, Magdalena, Kovacs, Levente, Pietras, Zbigniew, Puchinger, Martin, Dong, Gang, Dadlez, Michal, Glover, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009671/
https://www.ncbi.nlm.nih.gov/pubmed/33704067
http://dx.doi.org/10.7554/eLife.57241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009671/
https://www.ncbi.nlm.nih.gov/pubmed/33704067
http://dx.doi.org/10.7554/eLife.57241

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