DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia

We performed a systematic analysis of blood DNA methylation profiles from 4483 participants from seven independent cohorts identifying differentially methylated positions (DMPs) associated with psychosis, schizophrenia, and treatment-resistant schizophrenia. Psychosis cases were characterized by sig...

Descripción completa

Detalles Bibliográficos
Autores principales: Hannon, Eilis, Dempster, Emma L, Mansell, Georgina, Burrage, Joe, Bass, Nick, Bohlken, Marc M, Corvin, Aiden, Curtis, Charles J, Dempster, David, Di Forti, Marta, Dinan, Timothy G, Donohoe, Gary, Gaughran, Fiona, Gill, Michael, Gillespie, Amy, Gunasinghe, Cerisse, Hulshoff, Hilleke E, Hultman, Christina M, Johansson, Viktoria, Kahn, René S, Kaprio, Jaakko, Kenis, Gunter, Kowalec, Kaarina, MacCabe, James, McDonald, Colm, McQuillin, Andrew, Morris, Derek W, Murphy, Kieran C, Mustard, Colette J, Nenadic, Igor, O'Donovan, Michael C, Quattrone, Diego, Richards, Alexander L, Rutten, Bart PF, St Clair, David, Therman, Sebastian, Toulopoulou, Timothea, Van Os, Jim, Waddington, John L, Sullivan, Patrick, Vassos, Evangelos, Breen, Gerome, Collier, David Andrew, Murray, Robin M, Schalkwyk, Leonard S, Mill, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009672/
https://www.ncbi.nlm.nih.gov/pubmed/33646943
http://dx.doi.org/10.7554/eLife.58430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009672/
https://www.ncbi.nlm.nih.gov/pubmed/33646943
http://dx.doi.org/10.7554/eLife.58430

Ejemplares similares