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Selenium supplementation inhibits IGF-1 signaling and confers methionine restriction-like healthspan benefits to mice
Methionine restriction (MR) dramatically extends the healthspan of several organisms. Methionine-restricted rodents have less age-related pathology and increased longevity as compared with controls, and recent studies suggest that humans might benefit similarly. Mechanistically, it is likely that th...
Autores principales: | Plummer, Jason D, Postnikoff, Spike DL, Tyler, Jessica K, Johnson, Jay E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009673/ https://www.ncbi.nlm.nih.gov/pubmed/33783357 http://dx.doi.org/10.7554/eLife.62483 |
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