Anti-fibrotic activity of a rho-kinase inhibitor restores outflow function and intraocular pressure homeostasis

Glucocorticoids are widely used as an ophthalmic medication. A common, sight-threatening adverse event of glucocorticoid usage is ocular hypertension, caused by dysfunction of the conventional outflow pathway. We report that netarsudil, a rho-kinase inhibitor, decreased glucocorticoid-induced ocular...

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Detalles Bibliográficos
Autores principales: Li, Guorong, Lee, Chanyoung, Read, A Thomas, Wang, Ke, Ha, Jungmin, Kuhn, Megan, Navarro, Iris, Cui, Jenny, Young, Katherine, Gorijavolu, Rahul, Sulchek, Todd, Kopczynski, Casey, Farsiu, Sina, Samples, John, Challa, Pratap, Ethier, C Ross, Stamer, W Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009676/
https://www.ncbi.nlm.nih.gov/pubmed/33783352
http://dx.doi.org/10.7554/eLife.60831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009676/
https://www.ncbi.nlm.nih.gov/pubmed/33783352
http://dx.doi.org/10.7554/eLife.60831

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