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Evidence of association between obesity and lower cerebral myelin content in cognitively unimpaired adults

BACKGROUND: Myelin loss is a central feature of several neurodegenerative diseases, including Alzheimer’s disease (AD). In animal studies, a link has been established between obesity and impairment of oligodendrocyte maturation, the cells that produce and maintain myelin. Although clinical magnetic...

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Detalles Bibliográficos
Autores principales: Bouhrara, Mustapha, Khattar, Nikkita, Elango, Palchamy, Resnick, Susan M., Ferrucci, Luigi, Spencer, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009848/
https://www.ncbi.nlm.nih.gov/pubmed/33483582
http://dx.doi.org/10.1038/s41366-021-00749-x