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Endothelial progenitor cells-derived exosomal microRNA-21-5p alleviates sepsis-induced acute kidney injury by inhibiting RUNX1 expression

The role of microRNA-21-5p (miR-21-5p) in sepsis-induced acute kidney injury (AKI) has been seldom discussed. Therefore, the objective of this present study was to investigate the mechanism of endothelial progenitor cells-derived exosomes (EPCs-exos) in sepsis-induced AKI via miR-21-5p/runt-related...

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Detalles Bibliográficos
Autores principales: Zhang, Yue, Huang, Hongdong, Liu, Wenhu, Liu, Sha, Wang, Xue Yan, Diao, Zong Li, Zhang, Ai Hua, Guo, Wang, Han, Xue, Dong, Xiaoqun, Katilov, Oleksandr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009943/
https://www.ncbi.nlm.nih.gov/pubmed/33785732
http://dx.doi.org/10.1038/s41419-021-03578-y