Novel Peptides Targeting the β-Clamp Rapidly Kill Planktonic and Biofilm Staphylococcus epidermidis Both in vitro and in vivo

Antimicrobial resistance is an increasing threat to global health and challenges the way we treat infections. Peptides containing the PCNA interacting motif APIM (APIM-peptides) were recently shown to bind to the bacterial PCNA homolog, the beta (β)-clamp, and to have both antibacterial and anti-mut...

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Detalles Bibliográficos
Autores principales: Raeder, Synnøve Brandt, Sandbakken, Erik Thorvaldsen, Nepal, Anala, Løseth, Kirsti, Bergh, Kåre, Witsø, Eivind, Otterlei, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009970/
https://www.ncbi.nlm.nih.gov/pubmed/33815313
http://dx.doi.org/10.3389/fmicb.2021.631557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009970/
https://www.ncbi.nlm.nih.gov/pubmed/33815313
http://dx.doi.org/10.3389/fmicb.2021.631557

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