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Novel Peptides Targeting the β-Clamp Rapidly Kill Planktonic and Biofilm Staphylococcus epidermidis Both in vitro and in vivo
Antimicrobial resistance is an increasing threat to global health and challenges the way we treat infections. Peptides containing the PCNA interacting motif APIM (APIM-peptides) were recently shown to bind to the bacterial PCNA homolog, the beta (β)-clamp, and to have both antibacterial and anti-mut...
Autores principales: | Raeder, Synnøve Brandt, Sandbakken, Erik Thorvaldsen, Nepal, Anala, Løseth, Kirsti, Bergh, Kåre, Witsø, Eivind, Otterlei, Marit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009970/ https://www.ncbi.nlm.nih.gov/pubmed/33815313 http://dx.doi.org/10.3389/fmicb.2021.631557 |
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