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Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer

Lineage plasticity, the ability of a cell to alter its identity, is an increasingly common mechanism of adaptive resistance to targeted therapy in cancer. An archetypal example is the development of neuroendocrine prostate cancer (NEPC) after treatment of prostate adenocarcinoma (PRAD) with inhibito...

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Detalles Bibliográficos
Autores principales: Baca, Sylvan C., Takeda, David Y., Seo, Ji-Heui, Hwang, Justin, Ku, Sheng Yu, Arafeh, Rand, Arnoff, Taylor, Agarwal, Supreet, Bell, Connor, O’Connor, Edward, Qiu, Xintao, Alaiwi, Sarah Abou, Corona, Rosario I., Fonseca, Marcos A. S., Giambartolomei, Claudia, Cejas, Paloma, Lim, Klothilda, He, Monica, Sheahan, Anjali, Nassar, Amin, Berchuck, Jacob E., Brown, Lisha, Nguyen, Holly M., Coleman, Ilsa M., Kaipainen, Arja, De Sarkar, Navonil, Nelson, Peter S., Morrissey, Colm, Korthauer, Keegan, Pomerantz, Mark M., Ellis, Leigh, Pasaniuc, Bogdan, Lawrenson, Kate, Kelly, Kathleen, Zoubeidi, Amina, Hahn, William C., Beltran, Himisha, Long, Henry W., Brown, Myles, Corey, Eva, Freedman, Matthew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010057/
https://www.ncbi.nlm.nih.gov/pubmed/33785741
http://dx.doi.org/10.1038/s41467-021-22139-7