Light control of the peptide-loading complex synchronizes antigen translocation and MHC I trafficking

Antigen presentation via major histocompatibility complex class I (MHC I) molecules is essential to mount an adaptive immune response against pathogens and cancerous cells. To this end, the transporter associated with antigen processing (TAP) delivers snippets of the cellular proteome, resulting fro...

Descripción completa

Detalles Bibliográficos
Autores principales: Brunnberg, Jamina, Herbring, Valentina, Günther Castillo, Esteban, Krüger, Heike, Wieneke, Ralph, Tampé, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010092/
https://www.ncbi.nlm.nih.gov/pubmed/33785857
http://dx.doi.org/10.1038/s42003-021-01890-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010092/
https://www.ncbi.nlm.nih.gov/pubmed/33785857
http://dx.doi.org/10.1038/s42003-021-01890-z

Ejemplares similares