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Light control of the peptide-loading complex synchronizes antigen translocation and MHC I trafficking
Antigen presentation via major histocompatibility complex class I (MHC I) molecules is essential to mount an adaptive immune response against pathogens and cancerous cells. To this end, the transporter associated with antigen processing (TAP) delivers snippets of the cellular proteome, resulting fro...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010092/ https://www.ncbi.nlm.nih.gov/pubmed/33785857 http://dx.doi.org/10.1038/s42003-021-01890-z |