Discovery of novel antituberculosis agents among 3-phenyl-5-(1-phenyl-1H-[1,2,3]triazol-4-yl)-[1,2,4]oxadiazole derivatives targeting aminoacyl-tRNA synthetases

Antibiotic resistance is a major problem of tuberculosis treatment. This provides the stimulus for the search of novel molecular targets and approaches to reduce or forestall resistance emergence in Mycobacterium tuberculosis. Earlier, we discovered a novel small-molecular inhibitor among 3-phenyl-5...

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Detalles Bibliográficos
Autores principales: Rybak, Mariia Yu., Balanda, Anatoliy O., Yatsyshyna, Anna P., Kotey, Igor. M., Starosyla, Sergiy A., Bdzhola, Volodymyr G., Lukash, Lubov L., Yarmoluk, Sergiy M., Tukalo, Michael A., Volynets, Galyna P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010095/
https://www.ncbi.nlm.nih.gov/pubmed/33785838
http://dx.doi.org/10.1038/s41598-021-86562-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010095/
https://www.ncbi.nlm.nih.gov/pubmed/33785838
http://dx.doi.org/10.1038/s41598-021-86562-y

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