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Effects of CRMP2 DNA Methylation in the Hippocampus on Depressive-Like Behaviors and Cytoskeletal Proteins in Rats

Chronic stress appears to alter DNA methylation and DNA methyltransferases (DNMTs) in brain regions related to emotion. Collapsin response mediator protein-2 (CRMP2) mediates the development of depression by regulating microtubule dynamics. In this study, rats were subjected to chronic unpredictable...

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Detalles Bibliográficos
Autores principales: Xiang, Dan, Sun, Siqi, Wang, Gaohua, Liu, Zhongchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010135/
https://www.ncbi.nlm.nih.gov/pubmed/33815064
http://dx.doi.org/10.3389/fncel.2021.644663