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Antibodies Targeting the Transferrin Receptor 1 (TfR1) as Direct Anti-cancer Agents
The transferrin receptor 1 (TfR1), also known as cluster of differentiation 71 (CD71), is a type II transmembrane glycoprotein that binds transferrin (Tf) and performs a critical role in cellular iron uptake through the interaction with iron-bound Tf. Iron is required for multiple cellular processes...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010148/ https://www.ncbi.nlm.nih.gov/pubmed/33815364 http://dx.doi.org/10.3389/fimmu.2021.607692 |