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Exosomal-mediated transfer of OIP5-AS1 enhanced cell chemoresistance to trastuzumab in breast cancer via up-regulating HMGB3 by sponging miR-381-3p

BACKGROUND: Long noncoding RNA OPA-interacting protein 5 antisense transcript 1 (OIP5-AS1) was confirmed to involve in the malignancy of breast cancer. However, whether exosomal OIP5-AS1 is implicated in trastuzumab resistance remains unclear. METHODS: The IC(50) value of cells to trastuzumab, cell...

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Detalles Bibliográficos
Autores principales: Yu, Qiang, Li, Yinmou, Peng, Shijun, Li, Jing, Qin, Xianxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010158/
https://www.ncbi.nlm.nih.gov/pubmed/33821219
http://dx.doi.org/10.1515/med-2021-0249