Network Analysis of the CSF Proteome Characterizes Convergent Pathways of Cellular Dysfunction in ALS

BACKGROUND: Amyotrophic lateral sclerosis is a clinical syndrome with complex biological determinants, but which in most cases is characterized by TDP-43 pathology. The identification in CSF of a protein signature of TDP-43 network dysfunction would have the potential to inform the identification of...

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Detalles Bibliográficos
Autores principales: Thompson, Alexander G., Gray, Elizabeth, Charles, Philip D., Hu, Michele T. M., Talbot, Kevin, Fischer, Roman, Kessler, Benedikt M., Turner, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010303/
https://www.ncbi.nlm.nih.gov/pubmed/33815045
http://dx.doi.org/10.3389/fnins.2021.642324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010303/
https://www.ncbi.nlm.nih.gov/pubmed/33815045
http://dx.doi.org/10.3389/fnins.2021.642324

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