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Network Analysis of the CSF Proteome Characterizes Convergent Pathways of Cellular Dysfunction in ALS
BACKGROUND: Amyotrophic lateral sclerosis is a clinical syndrome with complex biological determinants, but which in most cases is characterized by TDP-43 pathology. The identification in CSF of a protein signature of TDP-43 network dysfunction would have the potential to inform the identification of...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010303/ https://www.ncbi.nlm.nih.gov/pubmed/33815045 http://dx.doi.org/10.3389/fnins.2021.642324 |