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Cartilaginous fish class II genes reveal unprecedented old allelic lineages and confirm the late evolutionary emergence of DM

Cartilaginous fish (chimaeras, rays and sharks) are the most basal extant jawed vertebrates with an adaptive immune system based on the Major Histocompatibility Complex (MHC). Despite being a key taxon in the evolution of vertebrate adaptive immunity, no comprehensive characterization of MHC class I...

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Detalles Bibliográficos
Autores principales: Almeida, Tereza, Gaigher, Arnaud, Muñoz-Mérida, Antonio, Neves, Fabiana, Castro, L. Filipe C., Flajnik, Martin F., Ohta, Yuko, Esteves, Pedro J., Veríssimo, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010645/
https://www.ncbi.nlm.nih.gov/pubmed/33126081
http://dx.doi.org/10.1016/j.molimm.2020.10.003