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ENC1 Facilitates Colorectal Carcinoma Tumorigenesis and Metastasis via JAK2/STAT5/AKT Axis-Mediated Epithelial Mesenchymal Transition and Stemness

Ectodermal neural cortex 1 (ENC1) is an actin-binding protein and has been known to be upregulated in several cancers, but the molecular mechanisms through which it contributes to the pathology of CRC have largely been elusive. We utilized data mining and validated the aberrant expression of ENC1, f...

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Detalles Bibliográficos
Autores principales: Cui, Ying, Yang, Jiani, Bai, Yibing, Li, QingWei, Yao, Yuanfei, Liu, Chao, Wu, Feng, Zhang, Jingchun, Zhang, Yanqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010667/
https://www.ncbi.nlm.nih.gov/pubmed/33816464
http://dx.doi.org/10.3389/fcell.2021.616887