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LncRNA POU3F3 Contributes to Dacarbazine Resistance of Human Melanoma Through the MiR-650/MGMT Axis

Background: Alkylating agents are critical therapeutic options for melanoma, while dacarbazine (DTIC)-based chemotherapy showed poor sensitivity in clinical trials. Long non-coding RNAs (lncRNAs) were highlighted in the progression of malignant tumors in recent years, whereas little was known about...

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Detalles Bibliográficos
Autores principales: Wu, Kai, Wang, Qiang, Liu, Yu-Lin, Xiang, Zhuo, Wang, Qing-Qing, Yin, Li, Liu, Shun-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010678/
https://www.ncbi.nlm.nih.gov/pubmed/33816296
http://dx.doi.org/10.3389/fonc.2021.643613