Inhibition of TGF-β/Smad3 Signaling Disrupts Cardiomyocyte Cell Cycle Progression and Epithelial–Mesenchymal Transition-Like Response During Ventricle Regeneration

Unlike mammals, zebrafish can regenerate injured hearts even in the adult stage. Cardiac regeneration requires the coordination of cardiomyocyte (CM) proliferation and migration. The TGF-β/Smad3 signaling pathway has been implicated in cardiac regeneration, but the molecular mechanisms by which this...

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Detalles Bibliográficos
Autores principales: Peng, Yuanyuan, Wang, Wenyuan, Fang, Yunzheng, Hu, Haichen, Chang, Nannan, Pang, Meijun, Hu, Ye-Fan, Li, Xueyu, Long, Han, Xiong, Jing-Wei, Zhang, Ruilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010688/
https://www.ncbi.nlm.nih.gov/pubmed/33816481
http://dx.doi.org/10.3389/fcell.2021.632372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010688/
https://www.ncbi.nlm.nih.gov/pubmed/33816481
http://dx.doi.org/10.3389/fcell.2021.632372

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