AKAP79/150 coordinates leptin-induced PKA signaling to regulate K(ATP) channel trafficking in pancreatic β-cells

The adipocyte hormone leptin regulates glucose homeostasis both centrally and peripherally. A key peripheral target is the pancreatic β-cell, which secretes insulin upon glucose stimulation. Leptin is known to suppress glucose-stimulated insulin secretion by promoting trafficking of K(ATP) channels...

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Detalles Bibliográficos
Autores principales: Cochrane, Veronica A., Yang, Zhongying, Dell'Acqua, Mark L., Shyng, Show-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010710/
https://www.ncbi.nlm.nih.gov/pubmed/33617875
http://dx.doi.org/10.1016/j.jbc.2021.100442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010710/
https://www.ncbi.nlm.nih.gov/pubmed/33617875
http://dx.doi.org/10.1016/j.jbc.2021.100442

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