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Interleukin-6 controls recycling and degradation, but not internalization of its receptors

Interleukin-6 (IL-6) is a cytokine implicated in proinflammatory as well as regenerative processes and acts via receptor complexes consisting of the ubiquitously expressed, signal-transducing receptor gp130 and the IL-6 receptor (IL-6R). The IL-6R is expressed only on hepatocytes and subsets of leuk...

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Detalles Bibliográficos
Autores principales: Flynn, Charlotte M., Kespohl, Birte, Daunke, Tina, Garbers, Yvonne, Düsterhöft, Stefan, Rose-John, Stefan, Haybaeck, Johannes, Lokau, Juliane, Aparicio-Siegmund, Samadhi, Garbers, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010714/
https://www.ncbi.nlm.nih.gov/pubmed/33610555
http://dx.doi.org/10.1016/j.jbc.2021.100434