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Interleukin-6 controls recycling and degradation, but not internalization of its receptors
Interleukin-6 (IL-6) is a cytokine implicated in proinflammatory as well as regenerative processes and acts via receptor complexes consisting of the ubiquitously expressed, signal-transducing receptor gp130 and the IL-6 receptor (IL-6R). The IL-6R is expressed only on hepatocytes and subsets of leuk...
Autores principales: | Flynn, Charlotte M., Kespohl, Birte, Daunke, Tina, Garbers, Yvonne, Düsterhöft, Stefan, Rose-John, Stefan, Haybaeck, Johannes, Lokau, Juliane, Aparicio-Siegmund, Samadhi, Garbers, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010714/ https://www.ncbi.nlm.nih.gov/pubmed/33610555 http://dx.doi.org/10.1016/j.jbc.2021.100434 |
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