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Femtomolar SARS-CoV-2 Antigen Detection Using the Microbubbling Digital Assay with Smartphone Readout Enables Antigen Burden Quantitation and Dynamics Tracking

BACKGROUND: Little is known about the dynamics of SARS-CoV-2 antigen burden in respiratory samples in different patient populations at different stages of infection. Current rapid antigen tests cannot quantitate and track antigen dynamics with high sensitivity and specificity in respiratory samples....

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Detalles Bibliográficos
Autores principales: Chen, Hui, Li, Zhao, Feng, Sheng, Wang, Anni, Richard-Greenblatt, Melissa, Hutson, Emily, Andrianus, Stefen, Glaser, Laurel J., Rodino, Kyle G., Qian, Jianing, Jayaraman, Dinesh, Collman, Ronald G., Glascock, Abigail, Bushman, Frederic D., Lee, Jae Seung, Cherry, Sara, Fausto, Alejandra, Weiss, Susan R., Koo, Hyun, Corby, Patricia M., O’Doherty, Una, Garfall, Alfred L., Vogl, Dan T., Stadtmauer, Edward A., Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010739/
https://www.ncbi.nlm.nih.gov/pubmed/33791710
http://dx.doi.org/10.1101/2021.03.17.21253847