Alternative splicing of OAS1 alters the risk for severe COVID-19

A locus containing OAS1/2/3 has been identified as a risk locus for severe COVID-19 among Europeans ancestry individuals, with a protective haplotype of ~75 kilobases derived from Neanderthals. Here, we show that among several potentially causal variants at this locus, a splice variant of OAS1 occur...

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Detalles Bibliográficos
Autores principales: Huffman, Jennifer, Butler-Laporte, Guillaume, Khan, Atlas, Drivas, Theodore G., Peloso, Gina M., Nakanishi, Tomoko, Verma, Anurag, Kiryluk, Krzysztof, Richards, J. Brent, Zeberg, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010745/
https://www.ncbi.nlm.nih.gov/pubmed/33791713
http://dx.doi.org/10.1101/2021.03.20.21254005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010745/
https://www.ncbi.nlm.nih.gov/pubmed/33791713
http://dx.doi.org/10.1101/2021.03.20.21254005

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