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Alternative splicing of OAS1 alters the risk for severe COVID-19
A locus containing OAS1/2/3 has been identified as a risk locus for severe COVID-19 among Europeans ancestry individuals, with a protective haplotype of ~75 kilobases derived from Neanderthals. Here, we show that among several potentially causal variants at this locus, a splice variant of OAS1 occur...
Autores principales: | Huffman, Jennifer, Butler-Laporte, Guillaume, Khan, Atlas, Drivas, Theodore G., Peloso, Gina M., Nakanishi, Tomoko, Verma, Anurag, Kiryluk, Krzysztof, Richards, J. Brent, Zeberg, Hugo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010745/ https://www.ncbi.nlm.nih.gov/pubmed/33791713 http://dx.doi.org/10.1101/2021.03.20.21254005 |
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