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HCV eradication with IFN-based therapy does not completely restore gene expression in PBMCs from HIV/HCV-coinfected patients

OBJECTIVE: To evaluate the impact of hepatitis C virus (HCV) elimination via interferon (IFN)-based therapy on gene expression profiles related to the immune system in HIV/HCV-coinfected patients. METHODS: We conducted a prospective study in 28 HIV/HCV-coinfected patients receiving IFN-based therapy...

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Detalles Bibliográficos
Autores principales: Brochado, Óscar, Martínez, Isidoro, Berenguer, Juan, Medrano, Luz, González-García, Juan, Jiménez-Sousa, María Ángeles, Carrero, Ana, Hontañón, Víctor, Navarro, Jordi, Guardiola, Josep M., Fernández-Rodríguez, Amanda, Resino, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010945/
https://www.ncbi.nlm.nih.gov/pubmed/33785040
http://dx.doi.org/10.1186/s12929-021-00718-6