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Exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by miR-192-5p/IL-17RA/Smad axis

BACKGROUND: Hypertrophic scar (HS) is a fibro-proliferative disorder of dermis after burn or trauma and usually leads to esthetic disfiguration and functionary impairment for patients. Emerging evidences demonstrated ADSC-Exo could alleviate the visceral fibrosis, but little attention had been paid...

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Detalles Bibliográficos
Autores principales: Li, Yan, Zhang, Jian, Shi, Jihong, Liu, Kaituo, Wang, Xujie, Jia, Yanhui, He, Ting, Shen, Kuo, Wang, Yunchuan, Liu, Jiaqi, Zhang, Wei, Wang, Tongtao, Zheng, Zhao, Hu, Dahai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010995/
https://www.ncbi.nlm.nih.gov/pubmed/33789737
http://dx.doi.org/10.1186/s13287-021-02290-0