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Impaired pattern separation in Tg2576 mice is associated with hyperexcitable dentate gyrus caused by Kv4.1 downregulation

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that causes memory loss. Most AD researches have focused on neurodegeneration mechanisms. Considering that neurodegenerative changes are not reversible, understanding early functional changes before neurodegeneration is critical to...

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Detalles Bibliográficos
Autores principales: Kim, Kyung-Ran, Kim, Yoonsub, Jeong, Hyeon-Ju, Kang, Jong-Sun, Lee, Sang Hun, Kim, Yujin, Lee, Suk-Ho, Ho, Won-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011083/
https://www.ncbi.nlm.nih.gov/pubmed/33785038
http://dx.doi.org/10.1186/s13041-021-00774-x