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A novel end-to-end method to predict RNA secondary structure profile based on bidirectional LSTM and residual neural network

BACKGROUND: Studies have shown that RNA secondary structure, a planar structure formed by paired bases, plays diverse vital roles in fundamental life activities and complex diseases. RNA secondary structure profile can record whether each base is paired with others. Hence, accurate prediction of sec...

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Detalles Bibliográficos
Autores principales: Wang, Linyu, Zhong, Xiaodan, Wang, Shuo, Zhang, Hao, Liu, Yuanning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011163/
https://www.ncbi.nlm.nih.gov/pubmed/33789581
http://dx.doi.org/10.1186/s12859-021-04102-x