Glioblastoma stem cell (GSC)-derived PD-L1-containing exosomes activates AMPK/ULK1 pathway mediated autophagy to increase temozolomide-resistance in glioblastoma

Temozolomide (TMZ)-resistance hampers the therapeutic efficacy of this drug for glioblastoma (GBM) treatment in clinic, and emerging evidences suggested that exosomes from GBM-derived stem cells (GSCs) contributed to this process, but the detailed mechanisms are still largely unknown. In the present...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Yong, Liu, Liang, Wang, Yan, Xiao, Shan, Mai, Rongkang, Zhu, Zifeng, Cao, Yiyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011168/
https://www.ncbi.nlm.nih.gov/pubmed/33789726
http://dx.doi.org/10.1186/s13578-021-00575-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011168/
https://www.ncbi.nlm.nih.gov/pubmed/33789726
http://dx.doi.org/10.1186/s13578-021-00575-8

Ejemplares similares