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Glioblastoma stem cell (GSC)-derived PD-L1-containing exosomes activates AMPK/ULK1 pathway mediated autophagy to increase temozolomide-resistance in glioblastoma

Temozolomide (TMZ)-resistance hampers the therapeutic efficacy of this drug for glioblastoma (GBM) treatment in clinic, and emerging evidences suggested that exosomes from GBM-derived stem cells (GSCs) contributed to this process, but the detailed mechanisms are still largely unknown. In the present...

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Detalles Bibliográficos
Autores principales:	Zheng, Yong, Liu, Liang, Wang, Yan, Xiao, Shan, Mai, Rongkang, Zhu, Zifeng, Cao, Yiyao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011168/ https://www.ncbi.nlm.nih.gov/pubmed/33789726 http://dx.doi.org/10.1186/s13578-021-00575-8

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