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Elevation of miR-302b prevents multiple myeloma cell growth and bone destruction by blocking DKK1 secretion
BACKGROUND: Myeloma bone disease (MBD) is a severe complication of multiple myeloma (MM) mainly due to an imbalance between enhanced osteoclast activity and reduced osteoblast function. Previous studies have demonstrated that miRNAs play a vital role in the osteogenic differentiation of mesenchymal...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011228/ https://www.ncbi.nlm.nih.gov/pubmed/33789678 http://dx.doi.org/10.1186/s12935-021-01887-y |