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Elevation of miR-302b prevents multiple myeloma cell growth and bone destruction by blocking DKK1 secretion

BACKGROUND: Myeloma bone disease (MBD) is a severe complication of multiple myeloma (MM) mainly due to an imbalance between enhanced osteoclast activity and reduced osteoblast function. Previous studies have demonstrated that miRNAs play a vital role in the osteogenic differentiation of mesenchymal...

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Detalles Bibliográficos
Autores principales: Wu, Zheyu, Zhang, Yufeng, Yang, Zhiqiang, Zhu, Yufan, Xie, Yuanlong, Zhou, Fuling, Cai, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011228/
https://www.ncbi.nlm.nih.gov/pubmed/33789678
http://dx.doi.org/10.1186/s12935-021-01887-y