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Early-life undernutrition induces enhancer RNA remodeling in mice liver

BACKGROUND: Maternal protein restriction diet (PRD) increases the risk of metabolic dysfunction in adulthood, the mechanisms during the early life of offspring are still poorly understood. Apart from genetic factors, epigenetic mechanisms are crucial to offer phenotypic plasticity in response to env...

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Detalles Bibliográficos
Autores principales: Wang, Yinyu, Mao, Yiting, Zhao, Yiran, Yi, Xianfu, Ding, Guolian, Yu, Chuanjin, Sheng, Jianzhong, Liu, Xinmei, Meng, Yicong, Huang, Hefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011416/
https://www.ncbi.nlm.nih.gov/pubmed/33789751
http://dx.doi.org/10.1186/s13072-021-00392-w