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Systematic Review of the Preclinical Technology Readiness of Orthopedic Gene Therapy and Outlook for Clinical Translation

Bone defects and improper healing of fractures are an increasing public health burden, and there is an unmet clinical need in their successful repair. Gene therapy has been proposed as a possible approach to improve or augment bone healing with the potential to provide true functional regeneration....

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Detalles Bibliográficos
Autores principales: Wilkinson, Piers, Bozo, Ilya Y., Braxton, Thomas, Just, Peter, Jones, Elena, Deev, Roman V., Giannoudis, Peter V., Feichtinger, Georg A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011540/
https://www.ncbi.nlm.nih.gov/pubmed/33816447
http://dx.doi.org/10.3389/fbioe.2021.626315