Effect of Epidermal Growth Factor Treatment and Polychlorinated Biphenyl Exposure in a Dietary-Exposure Mouse Model of Steatohepatitis

BACKGROUND: Polychlorinated biphenyls (PCBs) are signaling disrupting chemicals that exacerbate nonalcoholic steatohepatitis (NASH) in mice. They are epidermal growth factor receptor (EGFR) inhibitors that enhance hepatic inflammation and fibrosis in mice. OBJECTIVES: This study tested the hypothesi...

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Detalles Bibliográficos
Autores principales: Hardesty, Josiah E., Wahlang, Banrida, Prough, Russell A., Head, Kim Z., Wilkey, Daniel, Merchant, Michael, Shi, Hongxue, Jin, Jian, Cave, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011667/
https://www.ncbi.nlm.nih.gov/pubmed/33788613
http://dx.doi.org/10.1289/EHP8222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011667/
https://www.ncbi.nlm.nih.gov/pubmed/33788613
http://dx.doi.org/10.1289/EHP8222

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