Artificial intelligence and leukocyte epigenomics: Evaluation and prediction of late-onset Alzheimer’s disease

We evaluated the utility of leucocyte epigenomic-biomarkers for Alzheimer’s Disease (AD) detection and elucidates its molecular pathogeneses. Genome-wide DNA methylation analysis was performed using the Infinium MethylationEPIC BeadChip array in 24 late-onset AD (LOAD) and 24 cognitively healthy sub...

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Detalles Bibliográficos
Autores principales: Bahado-Singh, Ray O., Vishweswaraiah, Sangeetha, Aydas, Buket, Yilmaz, Ali, Metpally, Raghu P., Carey, David J., Crist, Richard C., Berrettini, Wade H., Wilson, George D., Imam, Khalid, Maddens, Michael, Bisgin, Halil, Graham, Stewart F., Radhakrishna, Uppala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011726/
https://www.ncbi.nlm.nih.gov/pubmed/33788842
http://dx.doi.org/10.1371/journal.pone.0248375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011726/
https://www.ncbi.nlm.nih.gov/pubmed/33788842
http://dx.doi.org/10.1371/journal.pone.0248375

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