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Artificial intelligence and leukocyte epigenomics: Evaluation and prediction of late-onset Alzheimer’s disease
We evaluated the utility of leucocyte epigenomic-biomarkers for Alzheimer’s Disease (AD) detection and elucidates its molecular pathogeneses. Genome-wide DNA methylation analysis was performed using the Infinium MethylationEPIC BeadChip array in 24 late-onset AD (LOAD) and 24 cognitively healthy sub...
Autores principales: | Bahado-Singh, Ray O., Vishweswaraiah, Sangeetha, Aydas, Buket, Yilmaz, Ali, Metpally, Raghu P., Carey, David J., Crist, Richard C., Berrettini, Wade H., Wilson, George D., Imam, Khalid, Maddens, Michael, Bisgin, Halil, Graham, Stewart F., Radhakrishna, Uppala |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011726/ https://www.ncbi.nlm.nih.gov/pubmed/33788842 http://dx.doi.org/10.1371/journal.pone.0248375 |
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