Assessing the co-variability of DNA methylation across peripheral cells and tissues: Implications for the interpretation of findings in epigenetic epidemiology

Most epigenome-wide association studies (EWAS) quantify DNA methylation (DNAm) in peripheral tissues such as whole blood to identify positions in the genome where variation is statistically associated with a trait or exposure. As whole blood comprises a mix of cell types, it is unclear whether trait...

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Detalles Bibliográficos
Autores principales: Hannon, Eilis, Mansell, Georgina, Walker, Emma, Nabais, Marta F., Burrage, Joe, Kepa, Agnieszka, Best-Lane, Janis, Rose, Anna, Heck, Suzanne, Moffitt, Terrie E., Caspi, Avshalom, Arseneault, Louise, Mill, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011804/
https://www.ncbi.nlm.nih.gov/pubmed/33739972
http://dx.doi.org/10.1371/journal.pgen.1009443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011804/
https://www.ncbi.nlm.nih.gov/pubmed/33739972
http://dx.doi.org/10.1371/journal.pgen.1009443

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