Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1–13)-NH(2)

[Image: see text] Nociceptin/orphanin FQ (N/OFQ) controls different biological functions via selective stimulation of the N/OFQ peptide (NOP) receptor. The pleiotropic actions of N/OFQ may limit the development of NOP ligands as innovative drugs in different therapeutic areas. The pharmacological co...

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Detalles Bibliográficos
Autores principales: Pacifico, Salvatore, Ferrari, Federica, Albanese, Valentina, Marzola, Erika, Neto, Joaquim Azevedo, Ruzza, Chiara, Calò, Girolamo, Preti, Delia, Guerrini, Remo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011926/
https://www.ncbi.nlm.nih.gov/pubmed/32901477
http://dx.doi.org/10.1021/acs.jmedchem.9b02057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011926/
https://www.ncbi.nlm.nih.gov/pubmed/32901477
http://dx.doi.org/10.1021/acs.jmedchem.9b02057

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