An unexpected role for p53 in regulating cancer cell–intrinsic PD-1 by acetylation

Cancer cell–intrinsic programmed cell death protein-1 (PD-1) has emerged as a tumor regulator in an immunity-independent manner, but its precise role in modulating tumor behaviors is complex, and how PD-1 is regulated in cancer cells is largely unknown. Here, we identified PD-1 as a direct target of...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Zhijie, Kon, Ning, Liu, Yajing, Xu, Wenbin, Wen, Jia, Yao, Han, Zhang, Mi, Wu, Zhen, Yan, Xiaojun, Zhu, Wei-Guo, Gu, Wei, Wang, Donglai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011965/
https://www.ncbi.nlm.nih.gov/pubmed/33789902
http://dx.doi.org/10.1126/sciadv.abf4148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011965/
https://www.ncbi.nlm.nih.gov/pubmed/33789902
http://dx.doi.org/10.1126/sciadv.abf4148

Ejemplares similares