Depolarizing GABA(A) current in the prefrontal cortex is linked with cognitive impairment in a mouse model relevant for schizophrenia

Cognitive impairment in schizophrenia (CIAS) is the most critical predictor of functional outcome. Limited understanding of the cellular mechanisms of CIAS hampers development of more effective treatments. We found that in subchronic phencyclidine (scPCP)–treated mice, an animal model that mimics CI...

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Detalles Bibliográficos
Autores principales: Kim, Haram R., Rajagopal, Lakshmi, Meltzer, Herbert Y., Martina, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011979/
https://www.ncbi.nlm.nih.gov/pubmed/33789887
http://dx.doi.org/10.1126/sciadv.aba5032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011979/
https://www.ncbi.nlm.nih.gov/pubmed/33789887
http://dx.doi.org/10.1126/sciadv.aba5032

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