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Synaptotagmin-7 places dense-core vesicles at the cell membrane to promote Munc13-2- and Ca(2+)-dependent priming
Synaptotagmins confer calcium-dependence to the exocytosis of secretory vesicles, but how coexpressed synaptotagmins interact remains unclear. We find that synaptotagmin-1 and synaptotagmin-7 when present alone act as standalone fast and slow Ca(2+)-sensors for vesicle fusion in mouse chromaffin cel...
Autores principales: | Tawfik, Bassam, Martins, Joana S, Houy, Sébastien, Imig, Cordelia, Pinheiro, Paulo S, Wojcik, Sonja M, Brose, Nils, Cooper, Benjamin H, Sørensen, Jakob Balslev |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012061/ https://www.ncbi.nlm.nih.gov/pubmed/33749593 http://dx.doi.org/10.7554/eLife.64527 |
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