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Zika virus NS3 protease induces bone morphogenetic protein-dependent brain calcification in human fetuses

The most frequent fetal birth defect associated with prenatal Zika virus (ZIKV) infection is brain calcification, which in turn may potentially affect neurological development in infants. Understanding the mechanism could inform the development of potential therapies against prenatal ZIKV brain calc...

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Detalles Bibliográficos
Autores principales: Chen, Weiqiang, Foo, Suan-Sin, Hong, Eunjin, Wu, Christine, Lee, Wai-Suet, Lee, Shin-Ae, Evseenko, Denis, Lopes Moreira, Maria Elisabeth, García-Sastre, Adolfo, Cheng, Genhong, Nielsen-Saines, Karin, Brasil, Patrícia, Avvad-Portari, Elyzabeth, Jung, Jae U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012254/
https://www.ncbi.nlm.nih.gov/pubmed/33510473
http://dx.doi.org/10.1038/s41564-020-00850-3