A novel knockout mouse for the small EDRK-rich factor 2 (Serf2) showing developmental and other deficits

The small EDRK-rich factor 2 (SERF2) is a highly conserved protein that modifies amyloid fibre assembly in vitro and promotes protein misfolding. However, the role of SERF2 in regulating age-related proteotoxicity remains largely unexplored due to a lack of in vivo models. Here, we report the genera...

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Detalles Bibliográficos
Autores principales: Cleverley, Karen, Lee, Weaverly Colleen, Mumford, Paige, Collins, Toby, Rickman, Matthew, Cunningham, Thomas J., Cleak, James, Mianne, Joffrey, Szoke-Kovacs, Zsombor, Stewart, Michelle, Teboul, Lydia, Maduro, Cheryl, Wells, Sara, Wiseman, Frances K., Fisher, Elizabeth M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012326/
https://www.ncbi.nlm.nih.gov/pubmed/33713180
http://dx.doi.org/10.1007/s00335-021-09864-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012326/
https://www.ncbi.nlm.nih.gov/pubmed/33713180
http://dx.doi.org/10.1007/s00335-021-09864-6

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