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Efficacy and safety of PEGylated exenatide injection (PB-119) in treatment-naive type 2 diabetes mellitus patients: a Phase II randomised, double-blind, parallel, placebo-controlled study

AIMS/HYPOTHESIS: Glucagon-like peptide 1 receptor agonists (GLP-1 RA) such as exenatide are used as monotherapy and add-on therapy for maintaining glycaemic control in patients with type 2 diabetes mellitus. The current study investigated the safety and efficacy of once-weekly PB-119, a PEGylated ex...

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Detalles Bibliográficos
Autores principales: Ji, Linong, Du, Ying, Xu, Min, Zhou, Xiangjun, Mo, Zhaohui, Ma, Jianhua, Li, Jiarui, Li, Yufeng, Lin, Jingna, Wang, Yanjun, Yang, Jing, Song, Weihong, Jin, Hui, Pang, Shuguang, Liu, Hui, Li, Ping, Liu, Jie, Yao, Minxiu, Li, Wenhui, Jiang, Xiaohong, Shen, Feixia, Geng, Houfa, Zhou, Haifeng, Ran, Jianmin, Lei, Minxiang, Du, Yinghong, Ye, Shandong, Guan, Qingbo, Lv, Wenshan, Tan, Huiwen, Chen, Tao, Yang, Jinkui, Qin, Guijun, Li, Shiyun, Chen, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012337/
https://www.ncbi.nlm.nih.gov/pubmed/33687487
http://dx.doi.org/10.1007/s00125-021-05392-9